Predicting injuries before they occur, personalizing treatments based on real movement, and bringing advanced biomechanics from the lab to the patient’s home—this is the technological leap proposed by SMART REHABI II, a project that combines digital twins, artificial intelligence, and biomechanical and genetic data to transform rehabilitation and sports performance.
The initiative brings together advances in podiatry, biomechanics, genetics, epigenetics, and AI with the goal of improving functional movement assessment, optimizing exercise plans, and reducing injury risk for both athletes and patients undergoing rehabilitation. At the heart of the project is the development of a digital twin of a biomechanical laboratory, a system capable of replicating and analyzing human body behavior based on real data captured from the patient.
The system is powered by information from inertial sensors and clinical assessment data, enabling the capture of kinematic and kinetic parameters during real movement and validating AI algorithms with an unprecedented level of accuracy.
One of the project’s main innovations is the integration of genetic and epigenetic variables with biomechanical data, opening the door to precision medicine applied to movement. Thanks to this combination, SMART REHABI II will be able to generate predictive models that help anticipate injury risks and tailor treatments to each individual’s unique profile.
The project also includes a home-based version of the system, using only two inertial sensors, allowing the patient’s home to become an extension of the laboratory and expanding access to advanced movement assessments beyond clinical or professional sports environments.
SMART REHABI II is led by Podoactiva and includes contributions from Origen Genetics, Arahealth, and the Global Sports Innovation Center (GSIC), which supports its international projection. The initiative was awarded first place in the 2025 call of the Ministry of Industry and Tourism under the Innovative Business Groups program.
With this project, innovation in health and sports takes a decisive step toward more predictive, personalized, and accessible models—bringing elite technologies closer to an increasingly broad audience.
